碩士生導師

徐甲坤，男，1984年1月生人，于2011年9月獲日本名古屋大學生物無機化學專業博士學位，現任中國水產科學研究院黃海水產研究所科研處副處長，研究員，研究生導師。主要從事生物催化與轉化等方面的研究，主持國家自然科學基金（面上、青年）、科技部“高端外國專家引進計劃”項目、農業農村部農業國際交流合作項目、山東省重點研發計劃等10余項項目；在ACS Catalysis、Journal of Hazardous Materials、Biosensors and Bioelectronics、International Journal of Biological Macromolecules、Catalysis Science&Technology、Chemistry–A European Journal等國際知名期刊發表論文60余篇，其中第一/通訊作者SCI 40余篇；獲授權國家發明專利10余項（第一發明人6項）；主編副主編出版著作3部；入選中國水產科學研究院“百名英才培育計劃”、中國水產科學研究院“青年英才”拔尖人才，榮獲山東省海洋與漁業科學技術獎青年科技獎、中國水產科學研究院黃海水產研究所青年科技獎；擔任中國水產科學研究院海洋生物酶工程創新團隊副首席；兼任亞太水產養殖中心網（NACA）技術指導委員會委員、中國水產學會海水養殖分會秘書長、中國海洋大學校友高級專家協會副秘書長，山東大學、中國海洋大學、上海海洋大學、青島科技大學等高校研究生導師。

聯系電話：13869828530，0532-85812670

通訊地址：山東省青島市市南區南京路106號

郵政編碼：266071

E-mail：xujk@ysfri.ac.cn

代表性論著：

1. Ridong Yang, Osami Shoji, Yingwu Lin, Fang Wang, Hongxia Che, Jiakun Xu^*, Construction of P450 scaffold biocatalysts for the biodegradation of five chloroanilines， Journal of Hazardous Materials, 2025, 488, 137305.

2.Yadan Yang, Weikang Zhang, Fang Wang, Dong Li, Xiangmin Meng, Xiaochun Sun, Jiakun Xu*, Construction of biocatalysts based on P450BM3 for the degradation of non-steroidal anti-inflammatory drugs, Journal of Hazardous Materials, 2024, 480, 136097.

3. Weikang Zhang, Yingwu Lin, Xiangmin Meng, Qiaoning Wang, Lingxin Chen*, Jiakun Xu^*, Construction of a myoglobin scaffold-based biocatalyst for the biodegradation of sulfadiazine and sulfathiazole, Journal of Hazardous Materials, 2024, 465, 113147.

4. Sijia Zhao, Yingwu Lin, Jinghan Wang, Dong Li, Fang Wang, Osami Shoji, Jiakun Xu^*, Regioselective aromatic O-demethylation with an artificial P450BM3/sugar alcohol oxidase peroxygenase system, International Journal of Biological Macromolecules, 2025, 309, 142768.

5. Weikang Zhang, Yadan Yang, Xiangmin Meng,*, Fang Wang, Yingwu Lin*, Jiakun Xu^*, Construction of artificial peroxidase based on myoglobin scaffold for efficient degradation of meloxicam, Journal of Inorganic Biochemistry, 2025, 262, 112733.

6. Guangrong Wu, Jiakun Xu^*, Lijuan Sun, Yingfu Li, Shuqin Gao, Yingwu Lin^*, Application of engineered heme enzymes based on myoglobin with high peroxidase activity for efficient degradation of various emerging pollutants, Journal of Environmental Chemical Engineering, 2023, 11, 111471.

7. Bin Qiao^*, Jiakun Xu^*, Wenhao Yin, Wanmeng Xin, Lixin Ma, Jie Qiao^*, Yi Liu^*, “Aptamer-locker” DNA coupling with CRISPR/Cas12a-guided biosensing for high-efficiency melamine analysis, Biosensors and Bioelectronics, 2021, 183, 113233.

8. Yihui Jiang, Chunlan Wang, Nana Ma, Jie Chen, Chuanfei Liu, Fang Wang, Jiakun Xu^*, Zhiqi Cong^*, Regioselective aromatic O-demethylation with an artificial P450BM3 peroxygenase system, Catalysis Science &Technology, 2020, 10, 1219-1223.

9. Jiakun Xu, Chunlan Wang, Zhiqi Cong^*, Strategies for substrate-regulated p450 catalysis: from substrate engineering to co-catalysis, Chemistry–A European Journal, 2019, 25, 6853-6863.